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7 Gut–liver–hypothalamus axis and emerging mitigation strategies 7.1 A systems-level perspective on mycotoxin toxicity along the gut–liver–hypothalamus axis This review highlights the complex and systemic nature of mycotoxin toxicity, moving beyond a single-organ perspective toward an integrated “gut–liver–hypothalamus axis.” Current evidence indicates that mycotoxins such as aflatoxins, ochratoxins, and deoxynivalenol (DON) not only cause localized damage but also initiate a pathological cascade that begins with intestinal dysbiosis and culminates in systemic hormonal and neurological disruption
